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Perlane - Aesthetica

Perlane adds volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). Perlane can also add fullness and definition to lips in patients over 21 years old.*


What is Perlane?

Perlane® is made from non-animal stabilized hyaluronic acid (NASHA) gel. There are no animal products in this filler. Since hyaluronic acid is a natural substance found in the skin and other tissue, there is no need for a skin test when using Perlane® filler.

The hyaluronic acid in Perlane® supplements the body’s natural supply, which becomes depleted with age. Perlane® is biodegradable, so its effects are not permanent. The results of a Perlane® filler treatment tend to last six months to a year. This is much longer than the typical results of collagen injections, which may only last three to six months.

Unlike Botox® Cosmetic, Perlane® does not make you numb. Perlane®can be used in conjunction with Botox® Cosmetic, which neutralizes the muscles that create wrinkles, but Perlane® simply reduces the visibility of wrinkles and folds.

How does Perlane work?

Perlane® is injected into the skin with an ultra-fine needle. It plumps the skin to smooth away wrinkles and folds. Perlane’s® water-based formula binds molecules to help maintain volume. Perlane® is composed of hyaluronic acid, a natural substance that already exists in the body. The hyaluronic acid in Perlane® is a crystal clear gel that is chemically cross-linked (the long chemical strands are tied together) to delay breakdown by skin enzymes.

Who should use Perlane treatments?

If you would like to improve the contour of your facial skin, Perlane® may be for you. The hyaluronic acid in Perlane® can be used to improve the contour of facial skin and to reduce wrinkles, folds, scars and other facial skin depressions.

Perlane® may be right for you if you would like to correct or enhance the following:

  • Wrinkles
  • Worry lines, smile lines, crow’s feet, marionette lines & smoker’s lines
  • Lip fullness
  • Nasolabial folds
  • Chin augmentation
  • Cheek volume
  • Lips’ border
  • Acne scars

The big advantage of Perlane® is that it is a non-permanent and natural treatment. The chemical contains a natural bodily chemical which fills up the skin like normal tissues. The modeling and contouring effects appear natural.

Who should NOT use Perlane treatments?

Perlane® should not be used in patients who have severe allergies marked by a history of anaphylaxis, multiple severe allergies, or severe allergies to gram-positive bacterial proteins.

What results should I expect from Perlane injections?

Perlane® will help smooth moderate to severe facial wrinkles and folds. In a clinical study most patients needed one injection to achieve optimal wrinkle smoothing; about one-third of patients needed more than one injection to get a satisfactory result. The smoothing effect lasts about six months. Perlane® gradually disappears from the body without a trace.

How long does a Perlane treatment take?

Perlane® injections do not take long. Most injections can be performed within 30-45 minutes.

Are Perlane treatments safe?

Perlane® has been used safely by dermatologists and plastic surgeons since 2000. Perlane® was studied in multiple clinical studies resulting in high patient satisfaction. Side effects were mild. Most of the side effects went away in seven days. Perlane did not cause allergic reactions.

Perlane® requires no pretesting, but you should take a few precautions before being treated. Avoid using St. John’s Wort, high doses of Vitamin E supplements, aspirin, and other non-steroidal anti-inflammatory medications, such as ibuprofen prior to treatment, because these may increase bruising or bleeding at the injection site. Also, if you have previously suffered from facial cold sores, discuss this with your physician.

Are Perlane injections painful?

Perlane® is injected directly into the skin in tiny amounts by an ultra-fine needle. To help maximize your comfort, you should discuss the use of numbing medicines with your doctor before treatment.

How long are the results effective?

The results of Perlane® are immediate and lasting and recovery time is minimal. Perlane® dissolves and is absorbed by your body over time. Your results depend on personal factors like your skin’s structure, lifestyle, and age. Perlane® treatments last for between six and nine months, although individuals will have varied results.

How often can I get Perlane treatments?

Depending on the results you’d like, you can discuss maintenance with your doctor and the period between injections. Follow up injections typically need less Perlane® to achieve the results you want. Time between injections is typically 6 to 12 months.

Are there side effects from Perlane?

After receiving a Perlane® injection some common side effects may be pain, redness, swelling, itching, discoloration, and tenderness at the point of injection. These side effects typically subside within two days of the Perlane® injection procedure.

While more severe reactions are rare, occurring in only 1 of 2000 patients on average, some have experienced localized swelling at the injection point, thought to be brought on by hypersensitivity. Tenderness, redness, and very rarely acne-like formations have appeared. Reactions can typically occur only a few days after the injection, or as long as four weeks. When a reaction does occur, its average lifespan is only a few weeks, and is typically described as moderate and mild.

*Results may vary from person to person. Medical assessment by our Medical Director or Nurse Practitioners is required prior to treatment.